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As far as I can tell, TextPad does not support any Unicode encodings such as UTF-8 or UTF-16. It is dependant on a 8-bit encoding with a predetermined code page.

ak47wong wrote:You should probably let Sophos know instead.

I've already submitted a case to them. I'll post back anything they come back with.

I suggest you try MudGuard's bookmark approach.
You can adapt his approach to choose whichever lines you want to keep or remove. The approach by definition works on whole lines as you were asking for.

After running PortableWizard.exe in TextPad 6, my Sophos AV reported a Suspicious behaviour in the file with name: "HIPS/RenFileMod-001"

I'm sure it is benign but thought I would let you know